icon Advanced Polycystic Ovary Syndrome (PCOS) Blood Test
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Advanced Polycystic Ovary Syndrome (PCOS) Blood Test
Advanced PCOS Blood Test

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  • full PCOS test with specialist counseling
  • simple and low-cost test

Advanced Polycystic Ovary Syndrome (PCOS) Blood Test

A doctor's comments are included in this test. If you do not require a doctor's comments then you can opt out. In selecting this option, you agree that you have a qualified clinician who can interpret your results.

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This advanced Polycystic Ovary Syndrome (PCOS) profile covers diabetes, cholesterol, hormones, thyroid function, and AMH testing (anti-mullerian hormone).

Is it for you?

Are you suffering from polycystic ovaries (PCOS) symptoms such as irregular periods and abundant facial hair? Are you thinking about starting a family and worried that PCOS would make it difficult to conceive? Or have you already been diagnosed with PCOS and want to keep an eye on your risk of diabetes and high cholesterol? This advanced profile is for you if you want a full PCOS test with specialist counselling on what it means for your health and fertility.

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Hormones (7  Biomarker)

Every bodily function, including development, metabolism, reproduction, and sleep cycles, is controlled by hormones.

Your mood and energy levels, as well as your fertility and libido, can all be negatively impacted by even a slight hormonal imbalance. Chemical messengers known as hormones are produced in your glands and delivered into your bloodstream.

Your body receives instructions from them on how to control your appetite, growth, mood, and reproduction. In general, they maintain the body's equilibrium and functionality.

Hormone imbalances are frequently treated with hormone replacement therapy or by altering one's lifestyle. Throughout the day and for women during the menstrual cycle, hormone levels change.

LH

The pituitary gland produces the luteinizing hormone (LH), which is crucial for both male and female reproduction. It controls the menstrual cycle in women and peaks just before ovulation. It increases testosterone production in men.

FSH

The pituitary gland produces the hormone follicle stimulating hormone (FSH), which is crucial for both men and women in the development of sperm and eggs.

FSH increases the growth of follicles within the ovaries in the first half of the menstrual cycle in women.

Oestradiol levels will rise thanks to each of these follicles. Follicle stimulating hormone levels fall throughout the second half of the menstrual cycle as one follicle becomes dominant and is discharged by the ovary (ovulation).

In men, FSH stimulates immature sperm cells to mature into sperm by acting on the seminiferous tubules of the testicles.

Testosterone

A hormone called testosterone is responsible for male features. It plays a part in controlling bone mass, fat distribution, muscular mass, strength, the creation of red blood cells, and the production of sperm in men.

It also helps to regulate sex drive. Men's testicles and, to a much lesser extent, women's ovaries both produce testosterone. Although lower than normal amounts of testosterone can occur at any age and can result in low libido, erectile dysfunction, difficulties gaining and retaining muscular mass, and lack of energy, testosterone levels in males naturally fall after the age of 30.

Even though testosterone levels in women are significantly lower than in men, it is still vital for the same reasons—it affects libido, how fat and muscle are distributed, and how red blood cells are formed.

Because reference ranges are dependent on the population being tested, they will all somewhat vary between laboratories. 95% of men will fall inside the usual range, which has been determined.

We follow the British Society for Sexual Medicine's (BSSM) recommendations for greater consistency, which state that low testosterone can be diagnosed when levels are consistently below the reference range and that levels below 12 nmol/L may also be considered low, particularly in men who also experience symptoms of low testosterone or who have low levels of free testosterone.

 Oestradiol

Oestradiol is a female steroid hormone that is made primarily in women's ovaries and only little in men's testicles.

The female reproductive system, breast tissue growth, and bone density are all influenced by this, the strongest of the three oestrogens. Oestradiol levels in premenopausal women fluctuate during the monthly cycle, reaching their highest point at ovulation.

Oestradiol levels in women decrease with ageing, peaking at menopause when the ovaries stop releasing eggs. Hot flashes, nocturnal sweats, and mood swings are just a few of the menopause symptoms that low oestradiol can bring on.

Osteoporosis can also result from low oestradiol.

Anti-Mullerian Hormone

The ovaries produce the hormone known as AMH, also known as anti-Mullerian hormone.

It is specifically made by the ovarian follicles that house the eggs. Levels might show whether a woman's ovarian reserve is high or low. Men's levels of anti-Mullerian hormone are not typically assessed.

Specialist reproductive clinics may use it to evaluate sperm production.

Free Testosterone Calc.

Only 2-3% of the testosterone that is circulating in the blood is free and available to cells; the majority is attached to proteins, particularly SHBG and albumin.

The method used in this test determines the ratio of free or unbound testosterone to total testosterone, SHBG, and albumin.

Prolactin

The pituitary gland produces the hormone prolactin, which is important for reproductive health.

Prolactin levels can skyrocket in pregnant and nursing women, and its main function is to boost milk production after delivery.

Proteins (4 Biomarker)

Proteins are essential for muscle growth as well as the operation of cells and tissues.

Blood proteins are measured to assist in the diagnosis of various illnesses, such as liver or kidney disease. It is common practise to analyse proteins to determine how much of a specific hormone is bound to a protein or free and thus available to your cells.

Proteins also transport other chemicals, such as hormones, throughout the blood. Dehydration is a common cause of elevated proteins, but they can also be a sign of other health issues.

A significant protein deficiency may be a sign of malnutrition or malabsorption.

SHBG

The majority of the sex hormones, including testosterone, oestrogen, and dihydrotestosterone (DHT), are bound to Sex Hormone Binding Globulin (SHBG), rendering them inactive in your cells.

The amount of free or unbound hormones, which are biologically active and available for usage, can be determined by measuring the level of SHBG in your blood.

Total Protein

The total protein in your blood is the sum of the proteins albumin and globulin. Among their many jobs, albumin and globulin keep blood in vessels, deliver nutrients, and combat infection.

A liver or renal problem as well as malnutrition may be indicated by abnormal levels.

Albumin

A protein called albumin is mostly produced in the liver. It aids in generating the osmotic pressure necessary to keep water in the blood.

It is crucial for tissue growth and repair and aids in the transportation of nutrients, medicines, and other chemicals via the blood. By evaluating albumin levels in the blood, we can determine how much hormone is available to your tissues.

Albumin also transports hormones throughout the body.

Globulin

The term "globulin" refers to a variety of proteins that the liver and immune system create. While certain globulins transport metals like iron in the blood, others bind with haemoglobin.

In addition, there is a specific class of globulin called an immunoglobulin, which is another name for an antibody and aids in the body's defence against infection.

Thyroid Hormones (1 Biomarker)

A gland at the front of your neck called the thyroid makes hormones that aid in regulating your metabolism.

Your thyroid may generate too little or too many thyroid hormones, and either situation can cause crippling symptoms.

Lethargy, weight gain, dry skin, and hair are typical symptoms of an underactive thyroid, while nervousness and anxiety are typical signs of an overactive thyroid, as well as weight loss.

Once detected, thyroid disorders can be treated, but even then, it's crucial to keep an eye on your thyroid hormone levels to make sure they stay at their ideal levels.

TSH

The thyroid is a gland located near the base of the neck that regulates several metabolic processes, including substrate turnover, heart function, muscle physiology, and energy expenditure.

Thyroid dysfunction can cause either overproduction of hormones (overactive) or the underproduction of hormones (underactive), both of which can lower athletic performance.

The pituitary gland produces Thyroid Stimulating Hormone (TSH), which stimulates the thyroid gland to create the thyroid hormones thyroxine (T4) and triiodothyronine (T3).As part of a neuroendocrine cascade, thyroid hormone synthesis occurs.

Thyrotropin-releasing hormone (TRH) is released first in the hypothalamus, where it causes the pituitary to release thyroid stimulating hormone (TSH).

To release the hormones T3 and T4, this attaches to thyroid gland cells (thyroxine). Additionally, peripheral tissues convert T4 into T3, the thyroid hormone with greater activity.

These hormones are essentially what regulate your body's metabolism.Negative feedback loops typically maintain a tight balance between all of these levels. Thyroid hormone over- or under-secretion can be a sign of abnormal thyroid function.

These disorders frequently have an autoimmune component, which can frequently be detected by looking at your thyroid antibodies in more sophisticated thyroid tests.


Cholesterol Status (6 Biomarkers)

A fatty molecule called cholesterol is present in the blood and is crucial for the proper functioning of the body's cells. But having too much cholesterol in your blood can seriously harm your health since it makes you more likely to experience a heart attack or stroke.
Numerous variables increase the risk of cardiovascular disease, and we continue to learn more about the intricate biochemical mechanisms that trigger a heart attack. However, even then, it is not so straightforward because there are various forms of cholesterol, some of which are more dangerous than others.
High levels of cholesterol have long been recognised to increase your risk.In addition to coming from the food we eat, cholesterol is also produced in the liver. Diet, family history, obesity, and inactivity all have a negative effect on cholesterol levels.

Total Cholesterol

In the organism, cholesterol is a necessary fat (lipid). Even though it has a terrible reputation, it performs a number of crucial tasks, such as creating cell membranes and a number of necessary hormones.
In addition to coming from the food we eat, cholesterol is also produced in the liver. The amount of both good (HDL) and bad (total) cholesterol in your blood is measured (LDL, VLDL and non HDL). When carbohydrate energy sources are scarce or for endurance activities, fats serve as the main energy source.Medium-chain fatty acids in particular are used extensively.
By examining the levels of the various forms of cholesterol, we can gain information into your health and cardiovascular risk. Cholesterol distributes fatty acids throughout the body (i.e. the buildup of cholesterol in blood vessels leading to blood vessel narrowing, heart attack and stroke).
The liver controls the amount of cholesterol in the body; it produces and eliminates it, and it also produces different lipoproteins that carry cholesterol throughout the body. It is these that the cholesterol test measures.

LDL cholesterol

Low density lipoprotein, often known as LDL cholesterol, is a lipid and protein molecule that carries triglycerides, cholesterol, and other fats to various bodily regions.

When fatty deposits build up inside artery walls due to an excess of LDL cholesterol, sometimes known as "bad cholesterol," this could result in atherosclerosis and heart disease.

Through food and exercise, your cholesterol levels can be dramatically reduced. Likewise, if you can raise your levels, you may be able to avoid developing significant, potentially fatal illnesses in the future.Results for HDL and LDL (and non-HDL) can be used as benchmarks and improvement targets. Regular exercise, especially cardio and weight training, will help lower LDL and raise HDL.

Cholesterol levels will also be optimised by a Mediterranean diet that is heavy in vegetables and oily fish and low in meat and dairy.

Non-HDL cholesterol

All of the cholesterol molecules that are not HDL (or "good" cholesterol") are referred to as non-HDL cholesterol. Therefore, it includes all of the potentially dangerous and non-protective cholesterol in your blood.

As a result, it is thought to be a more accurate indicator of cardiovascular risk than LDL cholesterol and total cholesterol. Less than 4 mmol/L of non-HDL cholesterol is advised. Through food and exercise, your cholesterol levels can be dramatically reduced. Likewise, if you can raise your levels, you may be able to avoid developing significant, potentially fatal illnesses in the future.

Results for HDL and LDL (and non-HDL) can be used as benchmarks and improvement targets.Regular exercise, especially cardio and weight training, will help lower LDL and raise HDL. Cholesterol levels will also be optimised by a Mediterranean diet that is heavy in vegetables and oily fish and low in meat and dairy.

HDL Cholesterol

High Density Lipoprotein, often known as HDL cholesterol, is a molecule that transfers cholesterol from the bloodstream to the liver, where it is broken down and expelled from the body as bile.

The term "good cholesterol" refers to HDL cholesterol. Through food and exercise, your cholesterol levels can be dramatically reduced. Likewise, if you can raise your levels, you may be able to avoid developing significant, potentially fatal illnesses in the future.

Results for HDL and LDL (and non-HDL) can be used as benchmarks and improvement targets. Regular exercise, especially cardio and weight training, will help lower LDL and raise HDL.

Cholesterol levels will also be optimised by a Mediterranean diet that is heavy in vegetables and oily fish and low in meat and dairy.

Total Cholesterol/HDL

By dividing your total cholesterol value by your HDL cholesterol level, you can get your cholesterol/HDL ratio. It serves as a gauge of cardiovascular risk since it provides useful information about the percentage of "good" cholesterol in your total cholesterol (i.e. high-density lipoprotein, HDL).

The cholesterol/HDL ratio is used by heart disease risk calculators (like QRisk) to estimate your risk of suffering a heart attack.

Triglycerides

Triglycerides are a type of lipid that move through the bloodstream. They are transported in the bloodstream by chylomicrons and VLDLs, two types of lipoproteins (very low density lipoproteins).

Following a meal, extra calories are converted by your body into triglycerides, which are subsequently carried to cells where they are stored as fat. Triglycerides are then released by your body when it needs energy.

Diabetes (1 Biomarker)

Type 2 diabetes is a metabolic condition that affects people of all ages more frequently. In the UK, up to one-third of persons are at risk of developing diabetes due to prediabetes.
It is brought about by the interaction of our genes and our way of life. Being overweight, eating poorly, and not exercising all increase the risk of having diabetes.
Early detection of diabetes is crucial because, even if your blood sugar has risen and you are at the prediabetic stage, you can still lower it by changing your lifestyle.
Once you have been diagnosed with diabetes, it is crucial to carefully control your blood glucose levels in order to prevent many of the serious complications that can harm your nerves, blood vessels, kidneys, and eyes.
Diabetes is a key contributor to shortened life expectancy and is a known risk factor for cancer, cardiovascular disease, and other illnesses.

HbA1c

Glycated haemoglobin, commonly known as haemoglobin A1c (HbA1c), is a longer-term indicator of blood glucose levels than a straightforward blood glucose test.

Your red blood cells' ability to attach glucose to haemoglobin plus the fact that these cells have an average lifespan of 12 to 16 weeks give us a decent idea of the typical quantity of sugar in your blood over the course of three months.

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