Zomig 2.5mg Tablets

Do not take Zomig:

• If you are allergic to zolmitriptan or any of the other ingredients of this medicine (listed in Section 6).
• If you have high blood pressure.
• If you have ever had heart problems, including a heart attack, angina (chest pain caused by exercise or effort), Prinzmetal’s angina (chest pain which happens at rest) or have experienced heart related symptoms such as shortness of breath or pressure over the chest.
• If you have had a stroke or short-lasting symptoms similar to stroke (transient ischaemic attack or TIA).
• If you are at the same time taking some other medicines for migraine (e.g. ergotamine or ergot-type medicines like dihydroergotamine and methysergide) or other triptan medicines for migraine (see Other medicines and Zomig for further information).

Do not take Zomig if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Zomig.

Warnings and precautions

Talk to your doctor or pharmacist before taking Zomig:

• If you are at risk of getting ischaemic heart disease (poor blood flow in the arteries of the heart). Your risk is greater if you smoke, have high blood pressure, high levels of cholesterol, diabetes or if anyone in your family has ischaemic heart disease.
• If you have been told that you have Wolff-Parkinson-White Syndrome (a type of abnormal heart beat).
• If you have ever had liver problems.
• If you have headaches which are not like your usual migraine headache.
• If you are taking any medicine for treatment of depression (see ‘Other medicines and Zomig’ for further information).

If you go into hospital tell the medical staff you are taking Zomig.

Zomig is not recommended for people aged over 65.

Children and adolescents

Zomig is not recommended in children and adolescents under 18 years.

As with other migraine treatments, using too much Zomig can cause daily headaches or can make your migraine headaches worse. Ask your doctor if you think that this is the case for you. You may need to stop taking Zomig to correct the problem.

Other medicines and Zomig

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes herbal medicines and medicines you buy without prescription.

In particular, tell your doctor if you are taking any of the following medicines:

Medicines for migraine

• If you take a triptan other than Zomig (such as sumatriptan or naratriptan) leave 24 hours before taking Zomig.
• After taking Zomig leave 24 hours before taking another triptan.
• If you take medicines containing ergotamine or ergot-type medicines (such as dihydroergotamine or methysergide), leave 24 hours before taking Zomig.
• After taking Zomig leave 6 hours before taking ergotamine or ergot-type medicines.

Medicines for depression

• Mono-Amine Oxidase Inhibitors, also known as MAOIs (such as moclobemide).
• SSRIs (selective serotonin reuptake inhibitors) such as fluoxetine, paroxetine, fluvoxamine or sertraline.
• SNRIs (serotonin norepinephrine reuptake inhibitors) such as venlafaxine or duloxetine. Serotonin syndrome is a rare, life-threatening condition that has been reported in some patients who took Zomig in combination with so called serotoninergic medicines (e.g. certain medicines for the treatment of depression). Signs of serotonin syndrome may be for example agitation, restlessness, fever, excessive sweating, tremor, uncoordinated movement of limbs or eyes, uncontrollable jerking of muscles, twitching and muscle rigidity. Your doctor may advise you on this.

Other medicines

• Cimetidine (for indigestion or stomach ulcers).
• A quinolone antibiotic (such as ciprofloxacin).

You should not take the herbal remedy St. John’s wort (Hypericum perforatum) at the same time as this medicine. If you already take a St. John’s wort preparation, stop taking it and mention this to your doctor at your next visit.

Zomig with food and drink

You can take Zomig with or without food. It does not affect the way that Zomig works.

Pregnancy, breast-feeding and fertility

It is not known if taking Zomig during pregnancy is harmful.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advise before taking this medicine.

Driving and using machines

During a migraine attack your reactions may be slower than usual. Bear this in mind when you drive or use any tools or machines.

Zomig is unlikely to affect driving or using tools or machines. However, it may make you feel sleepy. Wait to see how Zomig affects you before you try these activities.

Zomig contains Lactose

Zomig 2.5 mg tablets contain lactose which is a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium-free’.

If you take more Zomig than you should

If you take more Zomig than prescribed by your doctor, talk to your doctor or pharmacist straight away or go to the nearest hospital straight away. Take this medicine with you.

If you forget to take Zomig

• Do not take a double dose to make up for a forgotten dose.