Onglyza Tablets (Saxagliptin)

Onglyza or saxagliptin, along with diet and exercise, treats to lower blood sugar levels in patients with type 2 diabetes (a condition in which blood sugar is too high because the body does not produce or use insulin normally).

Onglyza is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amount of insulin produced by the body after meals when blood sugar is high. Onglyza is not used to treat type 1 diabetes (a condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated).

People with diabetes and high blood sugar eventually develop severe or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar help manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numbness, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. However, consult your doctor and other healthcare providers for suggestions on managing your diabetes.

Before you begin using Onglyza, make sure you read the instructions that come with each refill.

Take it as directed by your doctor. Usually, you should take Onglyza once per day.

Do not cut or split the tablet, take it as a whole. Follow the instructions of your doctor on how to properly use this medication.

To get the best results from Onglyza, you should take it regularly. To make sure you don't forget to take your dose, it is important to take Onglyza at the same time every day.

Follow the recommendations of your doctor for treatment, meals, and exercises.

One tablet of Onglyza per day is taken orally with a glass of water.

Your medical history, response to treatment and any other medications you are currently taking will determine the dosage of Onglyza that your doctor recommends.

Before taking Onglyza, tell your doctor or pharmacist if:

you are allergic to Onglyza is an allergic drug;
you are taking any prescription or non-prescription medications, vitamins and nutritional supplements, or herbal products;
you have drinking habits;
you have any history of pancreatitis (swelling in the pancreas), gallstones, liver disease, kidney disease, diabetes ketoacidosis (diabetic ketoacidosis), or heart failure;
you are pregnant, planning to be pregnant or breastfeeding;
you have surgery, such as dental surgery; or
you are hurt or get a fever.

These conditions may affect your blood sugar levels and the dosage of Onglyza that you may require.

Onglyza may cause changes in your blood sugar. Talk to your doctor to know the symptoms of low and high blood sugar and what to do if you have these symptoms.

Onglyza may cause side effects, like any other medicine. Inform your doctor if any of these symptoms are severe or do not go away:

sore throat
headache
joint pain
rash or hives
skin peeling
itching
swelling of the face, lips, tongue or throat
difficulty breathing or swallowing
hoarseness
the continuous pain which begins in the upper left or middle of the stomach but spreads to the back
nausea
loss of appetite
excessive tiredness
shortness of breath, especially when lying down
swelling of the feet, ankles, or legs
sudden weight gain

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