icon Lupus Anticoagulant Blood Test
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Lupus Anticoagulant Blood Test.
Lupus Anticoagulant Blood Test.
Lupus Anticoagulant Blood Test.

About Description

  • This blood test to investigate unexplained blood clots

Lupus Anticoagulant Blood Test


  •  £197.99
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Lupus anticoagulant is a protein that increases the risk of developing blood clots in both the veins and arteries. This blood test is for those wishing to investigate unexplained blood clots or those who have had recurrent miscarriages and are looking to investigate further.

5 Biomarkers:

Includes

Prothrombin Time (PT):

Prothrombin is a plasma protein produced by the liver. A prothrombin time test measures how long it takes for the blood to clot. Clotting is caused by a series of clotting factors activating each other, including the conversion of prothrombin to thrombin. 

Activated Partial Thromboplastin Time (APTT):

APTT, or Activated Partial Thromboplastin Time measures the speed at which blood clots in the body are formed, through a route known as the intrinsic pathway.

International Normalised Ratio (INR):

The international normalised ratio (INR) is a laboratory measurement of how long it takes for blood to form a clot. This can be useful to be able to determine the effects of anticoagulants such as warfarin on the clotting system.


dRVVT Normal Control:

Venom from the Russell's Viper snake causes blood to clot more quickly, whilst antiphospholipid syndrome slows down the speed at which blood clots. This test compares the time taken for a patient's blood sample to clot when it is mixed with Russell's Viper venom, and compares it to the speed for a control blood sample to clot .By dividing the time taken for the patient's sample to clot by the time taken for the control sample to clot a ratio is created, this helps to correct for the variability that can happen in reference ranges across laboratories. People who have antiphospholipid syndrome will clot more slowly, so the DRVVT ratio will be increased. DRVVT control is the time taken for the control sample to clot.

dRVVT Ratio to assess clotting function and potential risks linked to APS:

Venom from the Russell's Viper snake causes blood to clot more quickly, whilst antiphospholipid syndrome slows down the speed at which blood clots. This test compares the time taken for a patient's blood sample to clot when it is mixed with Russell's Viper venom, and compares it to the speed for a control blood sample to clot.By dividing the time taken for the patient's sample to clot by the time taken for the control sample to clot a ratio is created, this helps to correct for the variability that can happen in reference ranges across laboratories. People who have antiphospholipid syndrome will clot more slowly, so the DRVVT ratio will be increased.

Please note a Venous Blood Draw is require for this test and can be done at:
Patient Reception ,76 Wimpole Street ,London ,W1G 9RT

 

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Your bone marrow produces your clotting cells (platelets), which are crucial for regulating bleeding.

Thrombocytopenia is a condition that occurs when too few or too quickly damaged platelets are created. Immune problems, certain medications, liver illness, or continuous bleeding are all potential causes of this.

Thrombocytosis, often known as a high platelet count, can result from a number of illnesses, including problems with the bone marrow, infection, and inflammation.

The liver produces the plasma protein thrombin. The length of time it takes for the blood to clot is measured by a prothrombin time test. A number of clotting factors, including the transformation of prothrombin into thrombin, activate one another to cause clotting.

Activated Partial Thromboplastin Time (APTT), often known as the intrinsic pathway, is a measurement of how quickly blood clots develop within the body.

The length of time it takes for blood to clot is measured in a laboratory by the international normalised ratio (INR). Understanding the impact of anticoagulants like warfarin on the clotting system can be informative.

Blood clots more quickly in response to Russell's viper snake venom, while antiphospholipid syndrome causes blood clotting to take longer.

In this experiment, the rate at which a patient's blood sample clots when combined with Russell's viper venom is contrasted with the rate at which a control blood sample clots.

The variability in reference ranges between laboratories is reduced by dividing the time it takes for the patient's sample to clot by the time it takes for the control sample to clot.

Antiphospholipid syndrome patients will clot more slowly, increasing the DRVVT ratio. The DRVVT control measures how long it takes the control sample to clot.

Blood clots more quickly in response to Russell's viper snake venom, while antiphospholipid syndrome causes blood clotting to take longer.

In this experiment, the rate at which a patient's blood sample clots when combined with Russell's viper venom is contrasted with the rate at which a control blood sample clots.

The variability in reference ranges between laboratories is reduced by dividing the time it takes for the patient's sample to clot by the time it takes for the control sample to clot. Antiphospholipid syndrome patients will clot more slowly, increasing the DRVVT ratio.

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