Premique Low-Dose Tablets

Premique can only be prescribed by a doctor. Follow the instructions of your doctor. Always read the information leaflet included in the medication package. To treat your symptoms, your doctor will try to prescribe you a lower dose.

One tablet per day. Take it whole and drink a glass of water. To help you ensure you are taking the tablets correctly, there will be arrows beside them.

You can start Premique any time you like, even if you're not taking HRT. Premique is recommended for those who are switching from HRT products that give you a monthly bleeding. If you are switching from HRT that gives you a monthly bleeding to Premique, start Premique the day after you finish the course of the previous product.

Premique is a combination of active ingredients and female hormones. The weakest possible one will be prescribed by your doctor.

Each tablet contains 0.3mg conjugated oestrogens and 1.5mg medroxyprogesterone.

Premique tablets should be taken as soon as possible if you forget. You should throw away the missed tablet and resume taking the medication as usual.

Premique should not be taken in excess. Side effects include nausea, breast tenderness and abdominal pain. You should consult your doctor if you have concerns.

You should consult your doctor before taking Premique. If any of these conditions apply, you should not use Premique.

If you are suspect of developing breast cancer or have had it in the past,
If you have cancer that is sensitive to oestrogens
You should seek medical attention if you experience unexplained bleeding.
You have excessive thickening in your womb lining
If you've ever experienced a blood clot in your vein,
If you have a blood-clotting disorder
If you've ever been diagnosed with a blood-clotting disease in your arteries,
If you have had a liver disease in the past
A porphyria is a rare form of blood disorder.
If you have an allergy to any ingredient in this medication
If you're pregnant or nursing

You have to inform your doctor before using Premique if you have or have had experienced any of the following:

fibroids inside your womb
growth of the womb lining outside of your womb
blood clots or risk of developing blood clots
oestrogen-sensitive breast cancer or increased risk of oestrogen-sensitive breast cancer
high blood pressure
liver disorder
diabetes
removal of gallstones
severe headaches or migraines
an immune system disease that affects many organs
epilepsy
asthma
a sickness that affects the eardrum and hearing
high level of fat in your blood
fluid retention caused by kidney or cardiac problems

Premique, like many medicines with active ingredients can cause side effects or interactions with other medications. This can happen with certain medications like:

Epilepsy medications
Tuberculosis medicines
HIV medicine
Metyrapone (used to treat Cushing's syndrome).
Aminoglutethimide is used in the treatment for breast cancer and Cushing’s syndrome.
Herbal remedies that contain St John's Wort.
You should inform your doctor if you take any of these medications so they can recommend if Premique is compatible with your medicines.

HRT medication may increase your risk of breast cancer, excessive thickening of your womb lining, or cancer of the breast lining.

Blood clots are more common in HRT users than non-users, particularly in the first year. You should be alert for signs of blood clots and consult your doctor if there are any.

Premique may cause some side effects, which include:

Breast pain
Breakthrough bleeding or spotting
Vaginal inflammation
Period pain
Breast tenderness and swelling
Depression
Leg cramps, muscle and joint pains
Weight change (increase/decrease)

If any of these side effects persist or get worse, you should immediately inform your doctor. If you have any serious side effects, it is important to contact your doctor immediately.

Pharmacy4u is the best UK pharmacy to order Premique online. You only have to make a FREE consultation with our experienced prescribers, who are registered with the General Pharmaceutical Council. They will then review your consultation within minutes. Once your consultation is approved, the Online Pharmacy4U medical team will deliver Premique to you. Order before 3pm to receive your treatment the next day.

You no longer need assistance from your GP or your local pharmacy - we do all this online 4U for FREE here at Online Pharmacy4U.
More information on the FREE online consultations and delivery can be found in our How it works section.